The application of biological materials in everyday design is gaining traction and designers are encouraged to employ biological systems through biodesign and biophilia. However, there is a deficiency in the understanding of potential consumers’ perceptions. This paper compares the perception of non-designers as well as designers towards design-embedded bio-materials. Data was collected from 234 respondents using an online survey. The findings were gathered by evaluating perception in terms of desirability, practicality, aesthetically, and familiarity with living and non-living biomaterials.