This paper strikes an arc through C.P. Snow's influential 'Two Cultures' lecture at Cambridge University in 1959 through to Bruce Archer's assertion that design is the third culture of thinking in 1978 and positions how design thinking can contribute at a domain level to contemporary issues of the Anthropocene. After describing the separation of the three cultures of thinking, it considers different concepts for the third culture and how it may interact with the others. The core domain level practices of thinking cultures in the sciences, arts and humanities are explored and wroughting and wrighting is proposed for design. This contributes to a temporal model of knowledge production and exchange across domains. The value of governing and its application across domains is discussed and a proposal for a conceptual model of how inter-domain collaboration can address some of the problems of the Anthropocene is developed.

This is an Accepted Manuscript of an article published by Taylor & Francis in The Design Journal on 18 December 2019, available online: http://www.tandfonline.com/10.1080/14606925.2019.1693211.